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Taste receptors in the gut - A new target for health promoting properties in diet

Bo Ekstrand (Institutionen för biologi och bioteknik, Livsmedelsvetenskap) ; J. F. Young ; M. K. Rasmussen
Food Research International (0963-9969). Vol. 100 (2017), p. 1-8.
[Artikel, refereegranskad vetenskaplig]

In this review we describe a new target for food functionality, the taste receptors in the gastrointestinal tract. These receptors are involved in an intricate signalling network for monitoring of taste and nutrient intake, homeostasis and energy metabolism, and they are also an early warning system for toxic substances in our diet. Especially the receptors for bitter taste provide a new possibility to activate a number of health related signalling pathways, already at low concentrations of the active substance, without requiring uptake into the body and transport via the circulation. When ligands bind to these receptors, signalling is induced either via peptide hormones into the circulation to other organs in the body, or via nerve fibers directly to the brain.

Nyckelord: Taste receptors, Cell - cell signalling, Crosstalk, Taste, Functional food



Denna post skapades 2017-11-10.
CPL Pubid: 253071

 

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Institutioner (Chalmers)

Institutionen för biologi och bioteknik, Livsmedelsvetenskap

Ämnesområden

Farmakologi och toxikologi

Chalmers infrastruktur