CPL - Chalmers Publication Library
| Utbildning | Forskning | Styrkeområden | Om Chalmers | In English In English Ej inloggad.

Metagenomics of microbial and viral life in terrestrial geothermal environments

Andrea Strazzulli ; Salvatore Fusco (Institutionen för biologi och bioteknik, Industriell bioteknik) ; Beatrice Cobucci-Ponzano ; Marco Moracci ; Patrizia Contursi
Reviews in Environmental Science and Biotechnology (1569-1705). (2017)
[Artikel, refereegranskad vetenskaplig]

Geothermally heated regions of Earth, such as terrestrial volcanic areas (fumaroles, hot springs, and geysers) and deep-sea hydrothermal vents, represent a variety of different environments populated by extremophilic archaeal and bacterial microorganisms. Since most of these microbes thriving in such harsh biotopes, they are often recalcitrant to cultivation; therefore, ecological, physiological and phylogenetic studies of these microbial populations have been hampered for a long time. More recently, culture-independent methodologies coupled with the fast development of next generation sequencing technologies as well as with the continuous advances in computational biology, have allowed the production of large amounts of metagenomic data. Specifically, these approaches have assessed the phylogenetic composition and functional potential of microbial consortia thriving within these habitats, shedding light on how extreme physico-chemical conditions and biological interactions have shaped such microbial communities. Metagenomics allowed to better understand that the exposure to an extreme range of selective pressures in such severe environments, accounts for genomic flexibility and metabolic versatility of microbial and viral communities, and makes extreme- and hyper-thermophiles suitable for bioprospecting purposes, representing an interesting source for novel thermostable proteins that can be potentially used in several industrial processes.

Nyckelord: Hyperthermophiles Geothermal environments Microbial and viral metagenomics CRISPR Enzyme discovery



Denna post skapades 2017-06-19. Senast ändrad 2017-06-19.
CPL Pubid: 249971

 

Läs direkt!

Lokal fulltext (fritt tillgänglig)

Länk till annan sajt (kan kräva inloggning)