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Air bubbles are released by thoracic endograft deployment: An in vitro experimental study

Kamuran Inci ; Giasemi Koutouzi ; Valery Chernoray (Institutionen för tillämpad mekanik, Strömningslära) ; Anders Jeppsson ; Håkan Nilsson (Institutionen för tillämpad mekanik, Strömningslära) ; Mårten Falkenberg
SAGE Open Medicine (2050-3121). Vol. 4 (2016), p. 1-5.
[Artikel, refereegranskad vetenskaplig]

Purpose: Embolic stroke is a dreaded complication of thoracic endovascular aortic repair. The prevailing theory about its cause is that particulate debris from atherosclerotic lesions in the aortic wall are dislodged by endovascular instruments and embolize to the brain. An alternative source of embolism might be air trapped in the endograft delivery system. The aim of this experimental study was to determine whether air is released during deployment of a thoracic endograft. Methods: In an experimental benchtop study, eight thoracic endografts (five Medtronic Valiant Thoracic and three Gore TAG) were deployed in a water-filled transparent container drained from air. Endografts were prepared and deployed according to their instructions for use. Deployment was filmed and the volume of air released was collected and measured in a calibrated syringe. Results: Air was released from all the endografts examined. Air volumes ranged from 0.1 to 0.3 mL for Medtronic Valiant Thoracic and from <0.025 to 0.04 mL for Gore TAG. The largest bubbles had a diameter of approximately 3 mm and came from the proximal end of the Medtronic Valiant device. Conclusion: Air bubbles are released from thoracic endografts during deployment. Air embolism may be an alternative cause of stroke during thoracic endovascular aortic repair.

Nyckelord: Air, embolism, thoracic endovascular aortic repair, stroke, experimental



Denna post skapades 2016-12-12. Senast ändrad 2017-02-15.
CPL Pubid: 246060

 

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Institutioner (Chalmers)

Institutionen för kliniska vetenskaper, sektionen för kirurgi och kirurgisk gastroforskning, Avdelningen för gastrokirurgisk forskning och utbildning (GU)
Institutionen för tillämpad mekanik, Strömningslära (2005-2017)
Institutionen för medicin (GU)
Institutionen för kliniska vetenskaper, sektionen för onkologi, radiofysik, radiologi och urologi, Avdelningen för radiologi (GU)

Ämnesområden

Innovation och entreprenörskap (nyttiggörande)
Strömningsmekanik
Kardiologi
Kirurgi
Annan medicin och hälsovetenskap

Chalmers infrastruktur