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NaB integrated graphene oxide membranes for enhanced cell viability and stem cell properties of human adipose stem cells

Venkata Raghu Mokkapati (Institutionen för biologi och bioteknik, Systembiologi) ; Neslihan P. Tasli ; Zaeema Khan ; Ali Tufani ; Santosh Pandit (Institutionen för biologi och bioteknik, Systembiologi) ; Hikmet Budak ; Fikrettin Sahin
RSC Advances (2046-2069). Vol. 6 (2016), 61, p. 56159-56165.
[Artikel, refereegranskad vetenskaplig]

Here we present the integration of boron (NaB) with graphene oxide (GO) to develop a new class of membranes which are biocompatible and cost-effective for cell and tissue culture studies. Ethanol (EtOH) assisted the uniform dispersion of GO flakes on top of a glass substrate. We investigated the effect of a GO + NaB membrane on the growth and proliferation of hASCs. hASCs showed better cell viability on NaB integrated GO membranes compared to their respective controls. The concentrations of NaB and GO are 0.02% and 1/20 of stock (0.024%) respectively. To our knowledge this is the first time that enhanced cell proliferation and attachment ability of hASCs with NaB integrated GO membranes has been observed. Our study provides a platform for the development of 3D-GO scaffold systems combined with NaB in tissue engineering.



Denna post skapades 2016-07-05. Senast ändrad 2016-09-09.
CPL Pubid: 238978

 

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Institutioner (Chalmers)

Institutionen för biologi och bioteknik, Systembiologi

Ämnesområden

Bioinformatik och systembiologi

Chalmers infrastruktur