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A novel L-arabinose-responsive regulator discovered in the rice-blast fungus Pyricularia oryzae (Magnaporthe oryzae)

Sylvia Klaubauf (Institutionen för biologi och bioteknik, Industriell bioteknik) ; M. M. Zhou ; M. H. Lebrun ; R. P. de Vries ; E. Battaglia
Febs Letters (0014-5793). Vol. 590 (2016), 4, p. 550-558.
[Artikel, refereegranskad vetenskaplig]

In this study we identified the L-arabinose-responsive regulator of Pyricularia oryzae that regulates L-arabinose release and catabolism. Previously we identified the Zn2Cys6 transcription factor (TF), AraR, that has this role in the Trichocomaceae family (Eurotiales), but is absent in other fungi. Candidate Zn2Cys6 TF genes were selected according to their transcript profiles on L-arabinose. Deletion mutants of these genes were screened for their growth phenotype on L-arabinose. One mutant, named Delta ara1, was further analyzed. Our analysis demonstrated that Ara1 from P. oryzae is the functional analog of AraR from A. niger, while there is no significant sequence similarity between them.

Nyckelord: arabinanolytic regulator, pentose catabolic pathway, rice-blast fungus



Denna post skapades 2016-04-06. Senast ändrad 2016-12-06.
CPL Pubid: 234222

 

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Institutioner (Chalmers)

Institutionen för biologi och bioteknik, Industriell bioteknik

Ämnesområden

Medicinsk genetik

Chalmers infrastruktur