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Electronic polymers in lipid membranes

P.K. Johansson ; David Jullesson (Institutionen för biologi och bioteknik, Systembiologi) ; A. Elfwing ; S.I. Liin ; C. Musumeci ; E. Zeglio ; F. Elinder ; N. Solin ; O. Inganäs
Scientific Reports (2045-2322). Vol. 5 (2015),
[Artikel, refereegranskad vetenskaplig]

Electrical interfaces between biological cells and man-made electrical devices exist in many forms, but it remains a challenge to bridge the different mechanical and chemical environments of electronic conductors (metals, semiconductors) and biosystems. Here we demonstrate soft electrical interfaces, by integrating the metallic polymer PEDOT-S into lipid membranes. By preparing complexes between alkyl-ammonium salts and PEDOT-S we were able to integrate PEDOT-S into both liposomes and in lipid bilayers on solid surfaces. This is a step towards efficient electronic conduction within lipid membranes. We also demonstrate that the PEDOT-S@alkyl-ammonium:lipid hybrid structures created in this work affect ion channels in the membrane of Xenopus oocytes, which shows the possibility to access and control cell membrane structures with conductive polyelectrolytes.

Denna post skapades 2015-07-07. Senast ändrad 2015-07-07.
CPL Pubid: 219520


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Institutioner (Chalmers)

Institutionen för biologi och bioteknik, Systembiologi



Chalmers infrastruktur