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On the use of CR-39 PNTD with AFM analysis in measuring proton-induced target fragmentation particles

S. Kodaira ; T. Konishi ; H. Kitamura ; M. Kurano ; H. Kawashima ; Y. Uchihori ; T. Nishio ; N. Yasuda ; K. Ogura ; Lembit Sihver (Institutionen för teknisk fysik, Nukleär teknik) ; E. R. Benton
Nuclear Instruments & Methods in Physics Research Section B-Beam Interactions with Materials and Atoms (0168-583X). Vol. 349 (2015), p. 163-168.
[Artikel, refereegranskad vetenskaplig]

In addition to energy loss by ionization process, protons of energy >similar to 50 MeV, such as those used in proton radiotherapy, can undergo nuclear interactions with nuclei of Z > 1, resulting in the production, of short range (<20 gm), high-LET (linear energy transfer) target fragment particles. One of the few methods to detect these short-range particles is by means of CR-39 plastic nuclear track detector (PNTD) analyzed with an atomic force microscope (AFM). However, due to the LET-dependent angular sensitivity of CR-39 PNTD, multiple detectors exposed at a range of incident angles to the primary proton beam, must be analyzed in order to accurately determine the LET spectrum, absorbed dose and dose equivalent. The LET spectrum of 160 MeV proton-induced secondary particles was experimentally measured with CR-39 PNTDs, which were exposed at six different incident angles to take into account the intrinsic sensitivity of the critical angle for track registration. The irradiated detectors were chemically processed to remove a 1 gm thick volume of CR-39 PNTD. The measured LET range of short range tracks was from 15 key/mu m up to 1.5 MeV/mu m. The absorbed dose contribution (D-s/D-p) from secondary particles to primary proton dose was similar to 1%, while the dose equivalent contribution (H-s/D-p) was found to be similar to 20%. Analysis of CR-39 PNTD by AFM yielded similar to 60% higher value for absorbed dose compared to standard optical microscopy analysis.

Nyckelord: Proton therapy, Secondary particles, Target fragmentation, CR-39, AFM, Nuclear Track Detector, Biological Effectiveness, Charged-Particles

Denna post skapades 2015-06-10.
CPL Pubid: 218167


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Institutionen för teknisk fysik, Nukleär teknik (2006-2015)



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