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Rat brain kinematics and tissue strains associated to Diffuse Axonal Injuries induced by head rotational acceleration

Jacobo Antona-Makoshi (Institutionen för tillämpad mekanik, Fordonssäkerhet) ; Johan Davidsson (Institutionen för tillämpad mekanik, Fordonssäkerhet ; SAFER - Fordons- och Trafiksäkerhetscentrum ) ; Susumu Ejima
Proceedings of Computational Engineering Conference JSCES Vol. 18 (2013),
[Konferensbidrag, övrigt]

An anatomically detailed finite element model of a rat head-neck complex has been developed from medical images. The model incorporates material properties from tissue indentation test data captured in the coronal plane from seven brain regions to account for non-homogeneity. The local brain-skull relative displacement has been validated against local brain-slip experimental data in which a thin pin was entered the cortex and rigidly attached to the skull prior to impact. The model is being used to improve the understanding of brain rotational kinematics and to develop brain tissue injury thresholds for Diffuse Axonal Injuries as detected through immuno-histology.

Nyckelord: diffuse axonal injuries, finite element model, head rotational acceleration



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Denna post skapades 2014-01-13. Senast ändrad 2015-01-27.
CPL Pubid: 192247