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Validation of local brain kinematics of a novel rat brain finite element model under rotational acceleration and its application towards the clarification of Diffuse Axonal Injury mechanisms

Jacobo Antona-Makoshi (Institutionen för tillämpad mekanik, Fordonssäkerhet) ; Johan Davidsson (Institutionen för tillämpad mekanik, Fordonssäkerhet ; SAFER - Fordons- och Trafiksäkerhetscentrum ) ; Mårten Risling ; Susumu Ejima ; Koshiro Ono
Proceeding of JSAE Annual Congress, Yokohama, Japan 20135406, (2013)
[Konferensbidrag, övrigt]

Relative brain-skull displacement under head rotational acceleration in rats was evaluated experimentally. For this, a thin pin was entered the cortex and rigidly attached to the skull prior to impact. For peak rotational accelerations of 1.7 Mrad/s2, the pin scarred the brain cortex; 1.2 mm superficially and less centrally. These measurements were used to validate the brain kinematics of a new anatomically detailed FE model of the head-neck complex of a rat. This model is intended to be used to clarify brain loading mechanisms and to develop brain tissue injury threshold for Diffuse Axonal Injuries as detected through immune-histology.

Nyckelord: finite element method (FEM), injury mechanism, (safety), Diffuse Axonal Injuries



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Denna post skapades 2014-01-13. Senast ändrad 2015-01-27.
CPL Pubid: 192246