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BacMet: antibacterial biocide and metal resistance genes database

Chandan Pal ; Johan Bengtsson-Palme ; Christopher Rensing ; Erik Kristiansson (Institutionen för matematiska vetenskaper, matematisk statistik) ; D. G. Joakim Larsson
Nucleic Acids Research (0305-1048). Vol. 42 (2014), D1, p. D737-D743.
[Artikel, refereegranskad vetenskaplig]

Antibiotic resistance has become a major human health concern due to widespread use, misuse and overuse of antibiotics. In addition to antibiotics, antibacterial biocides and metals can contribute to the development and maintenance of antibiotic resistance in bacterial communities through co-selection. Information on metal and biocide resistance genes, including their sequences and molecular functions, is, however, scattered. Here, we introduce BacMet (http://bacmet.biomedicine.gu.se)-a manually curated database of antibacterial biocide-and metal-resistance genes based on an in-depth review of the scientific literature. The BacMet database contains 470 experimentally verified resistance genes. In addition, the database also contains 25 477 potential resistance genes collected from public sequence repositories. All resistance genes in the BacMet database have been organized according to their molecular function and induced resistance phenotype.



Denna post skapades 2013-11-21. Senast ändrad 2015-03-09.
CPL Pubid: 187209

 

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Institutioner (Chalmers)

Institutionen för biomedicin, avdelningen för infektionssjukdomar (GU)
Institutionen för matematiska vetenskaper, matematisk statistik (2005-2016)

Ämnesområden

Bioinformatik (beräkningsbiologi)
Biologiska vetenskaper

Chalmers infrastruktur