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Mindfulness based stress reduction study design of a longitudinal randomized controlled complementary intervention in women with breast cancer

Elisabeth Kenne Sarenmalm ; Lena B. Mårtensson ; Stig B Holmberg ; Bengt A. Andersson ; Anders Odén (Institutionen för matematiska vetenskaper, matematisk statistik) ; Ingrid Bergh
BMC Complementary and Alternative Medicine (1472-6882). Vol. 13 (2013), p. Article Number: 248.
[Artikel, refereegranskad vetenskaplig]

The stress of a breast cancer diagnosis and its treatment can produce a variety of psychosocial sequelae including impaired immune responses. Mindfulness Based Stress Reduction (MBSR) is a structured complementary program that incorporates meditation, yoga and mind-body exercises. Despite promising empirical evidence for the efficacy of MBSR, there is a need for randomized controlled trials (RCT). There is also a need for RCTs investigating the efficacy of psychosocial interventions on mood disorder and immune response in women with breast cancer. Therefore, the overall aim is to determine the efficacy of a Mindfulness Based Stress Reduction (MBSR) intervention on well-being and immune response in women with breast cancer. In this RCT, patients diagnosed with breast cancer, will consecutively be recruited to participate. Participants will be randomized into one of three groups: MBSR Intervention I (weekly group sessions + self-instructing program), MBSR Intervention II (self-instructing program), and Controls (non-MBSR). Data will be collected before start of intervention, and 3, 6, and 12 months and thereafter yearly up to 5 years. This study may contribute to evidence-based knowledge concerning the efficacy of MBSR to support patient empowerment to regain health in breast cancer disease. The present study may contribute to evidence-based knowledge concerning the efficacy of mindfulness training to support patient empowerment to regain health in a breast cancer disease. If MBSR is effective for symptom relief and quality of life, the method will have significant clinical relevance that may generate standard of care for patients with breast cancer.

Nyckelord: Breast cancer, Mindfulness based stress reduction, Randomized controlled trials, Well-being



Denna post skapades 2013-10-16. Senast ändrad 2016-07-18.
CPL Pubid: 185307

 

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Institutioner (Chalmers)

Institutionen för vårdvetenskap och hälsa (GU)
Institutionen för biomedicin, avdelningen för mikrobiologi och immunologi (GU)
Institutionen för matematiska vetenskaper, matematisk statistik (2005-2016)

Ämnesområden

Klinisk medicin

Chalmers infrastruktur