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Carbon-core silver-shell nanodots as sensitizers for phototherapy and radiotherapy

A. Kleinauskas ; Sandra Rocha (Institutionen för kemi- och bioteknik, Fysikalisk kemi) ; S. Sahu ; Y. P. Sun ; P. Juzenas
Nanotechnology (0957-4484). Vol. 24 (2013), 32,
[Artikel, refereegranskad vetenskaplig]

Spherical carbon nanoparticles (carbon nanodots) with a silver shell were investigated as potential sensitizing agents. The cytotoxicity of the combination of ultraviolet radiation or x-rays with the nanodots was examined in cancer cells in vitro. The cell viability decreased following the exposure to the radiation. The carbon nanodots enhanced the radiation effects by significantly reducing the amount of surviving cells compared to that of the cells exposed only to the radiation. Carbon-core silver-shell nanodots can be proposed as a bimodal sensitization platform for biological and medicinal applications employing non-ionizing or ionizing radiation.

Nyckelord: Cancer, Nanoparticles, Photocatalysis, Photosensitizer, Radiocatalysis, Radiosensitizer



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Denna post skapades 2013-09-02. Senast ändrad 2013-11-20.
CPL Pubid: 182630

 

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Institutioner (Chalmers)

Institutionen för kemi- och bioteknik, Fysikalisk kemi (2005-2014)

Ämnesområden

Nanovetenskap och nanoteknik
Fysikalisk kemi
Nanoteknik
Medicinsk bioteknologi

Chalmers infrastruktur