CPL - Chalmers Publication Library
| Utbildning | Forskning | Styrkeområden | Om Chalmers | In English In English Ej inloggad.

Site-specific adhesion of Staphylococcus epidermidis (RP12) in Ti-Al-V metal systems

B. L. Gabriel ; Julie Gold (Institutionen för teknisk fysik, Kemisk fysik) ; A. G. Gristina ; Bengt Kasemo (Institutionen för teknisk fysik, Kemisk fysik) ; Jukka Lausmaa (Institutionen för teknisk fysik, Kemisk fysik) ; C. Harrer ; Q. N. Myrvik
Biomaterials (0142-9612). Vol. 15 (1994), 8, p. 628-634.
[Artikel, refereegranskad vetenskaplig]

Staphylococcus epidermidis (RP12) adhesion patterns were studied on the following titanium (Ti)-aluminium (Al)-vanadium (V) metal systems: (i) microfabricated samples consisting of Ti, Al and V islands deposited onto Ti or V substrata, (ii) pure Ti, Al and V metals, and (iii) medical grade Ti6Al4-V alloy. All of these surfaces were covered with their respective oxides formed upon exposure of the metals to air. Quantitative analysis of the number of cells bound per unit area indicates that S. epidermidis (RP12) exhibits greatest adhesion to pure V surfaces. When exposed to surfaces having controlled spatial variations in chemical composition on the 10 mu m scale (microfabricated samples), the bacteria preferentially populate V islands versus Ti or Al substrata. In the case of the biphasic Ti6Al4V alloy, the bacteria tend to adhere to V-rich, mixed phase regions and phase boundaries. These findings demonstrate that enhanced and preferential adhesion of S. epidermidis (RP12) occurs on V surfaces in TI-Al-V metal systems and suggest that bacterial interactions are influenced by surface oxide composition.

Nyckelord: bacterial adhesion, microfabrication, titanium alloys, staphylococci, biomaterials, surfaces, oxides

Denna post skapades 2013-01-30. Senast ändrad 2013-01-31.
CPL Pubid: 172682


Läs direkt!

Länk till annan sajt (kan kräva inloggning)

Institutioner (Chalmers)

Institutionen för teknisk fysik, Kemisk fysik (1900-2015)


Kemisk fysik

Chalmers infrastruktur