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Highlights of selected recent electrochemical measurements in living systems

Raphaël Trouillon ; Maria I. Svensson ; Carina Berglund ; Ann-Sofie Cans (Institutionen för kemi- och bioteknik, Analytisk kemi) ; Andrew G Ewing (Institutionen för kemi- och bioteknik, Analytisk kemi)
Electrochimica Acta (0013-4686). Vol. 84 (2012), p. 84-95.
[Artikel, refereegranskad vetenskaplig]

Since the early work carried out by Ralph Adams in the 1970s, electrochemistry has been established as a powerful analytical tool for neuroscience. In this review, we focus on some novel and innovative methods for the electrochemical analysis of biological samples reported during the last five years. Recent findings in the neurochemistry of Drosophila melanogaster, a new and simple animal model, are summarized. A wealth of technical improvements of the electrode materials or of the instrumentation has been used to achieve higher sensitivity or robustness, to detect new biologically relevant analytes or simply to offer new experimental possibilities. Electrochemical imaging of exocytosis, in vivo or in vitro at the single cell level, is also summarized here. Finally, new perspectives and emerging technologies are discussed.

Nyckelord: Bioanalysis, Neurochemistry, Drosophila melanogaster, Electrochemical imaging, In vivo sensing, scan cyclic voltammetry, frog neuromuscular-junctions, carbon-fiber, microelectrodes, individual chromaffin cells, hydrogen-peroxide, intense, release, freeze-fracture, electroanalytical techniques, diamond, microelectrodes, transmitter release



Denna post skapades 2013-01-17. Senast ändrad 2015-02-26.
CPL Pubid: 171259

 

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Institutioner (Chalmers)

Institutionen för kemi och molekylärbiologi (GU)
Institutionen för kemi- och bioteknik, Analytisk kemi (2006-2014)

Ämnesområden

Elektrokemi

Chalmers infrastruktur