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A metabolic network of a phosphate-accumulating organism provides new insights into enhanced biological phosphorous removal

Sergio Bordel Velasco (Institutionen för kemi- och bioteknik, Systembiologi)
Water Science and Technology (0273-1223). Vol. 64 (2011), 12, p. 2410-2416.
[Artikel, refereegranskad vetenskaplig]

Here we present a metabolic network representing the central carbon metabolism as well as the synthesis of polyhydroxyalcanohates and the polyphosphate accumulation mechanisms of the bacterium Candidatus Accumulibacter phosphatis, which was previously identified from metagenomic studies in enhanced biological phosphorous removal sludges. The reconstructed metabolic network, together with flux balance analysis can be used to provide new insights into controversial aspects of the metabolism of phosphate-accumulating organisms and is also a tool that can be used in to help enhanced biological phosphorous removal (EBPR) process design and operation.

Nyckelord: enhanced biological phosphorous removal, flux balance analysis, metabolic networks, activated-sludge, waste-water, models

Denna post skapades 2012-04-10.
CPL Pubid: 156496


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Institutioner (Chalmers)

Institutionen för kemi- och bioteknik, Systembiologi (2008-2014)


Biologiska vetenskaper

Chalmers infrastruktur