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Size Distribution of Exhaled Particles in the Range from 0.01 to 2.0 µm

Helene Holmgren (Institutionen för kemi- och bioteknik, Oorganisk miljökemi) ; Evert Ljungström ; Ann-Charlotte Almstrand ; Björn Bake ; Anna-Carin Olin
Journal of Aerosol Science (0021-8502). Vol. 41 (2010), 5, p. 439-446.
[Artikel, refereegranskad vetenskaplig]

This study investigates the number size distribution of endogenously produced exhaled particles during tidal breathing and breathing with airway closure. This is the first time that the region below 0.4 µm has been investigated. The particle concentration was generally lower for tidal breathing than for airway closure, although the inter-individual variation was large. During tidal breathing, the size distribution peaks at around 0.07 µm. This peak is still present during the airway closure manoeuvre, but an additional broad and strong peak is found between 0.2 and 0.5 µm. This suggests that different mechanisms govern the generation of particles in the two cases. The particles produced from airway closure may be attributed to formation of film droplets in the distal bronchioles during inhalation. It is speculated that the very small particles are film droplets originating from the alveolar region.

Nyckelord: exhaled particles, size distribution, airway closure, tidal breathing

Denna post skapades 2011-11-01. Senast ändrad 2016-10-14.
CPL Pubid: 147964


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Institutioner (Chalmers)

Institutionen för kemi- och bioteknik, Oorganisk miljökemi (2005-2014)
Institutionen för kemi (2001-2011)
Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa (GU)
Institutionen för medicin (GU)


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On the Formation and Physical Behaviour of Exhaled Particles