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Bacterial cellulose-based materials and medical devices: current state and perspectives

N. Petersen ; Paul Gatenholm (Institutionen för kemi- och bioteknik, Polymerteknologi)
Applied Microbiology and Biotechnology (0175-7598). Vol. 91 (2011), 5, p. 1277-1286.
[Artikel, refereegranskad vetenskaplig]

Bacterial cellulose (BC) is a unique and promising material for use as implants and scaffolds in tissue engineering. It is composed of a pure cellulose nanofiber mesh spun by bacteria. It is remarkable for its strength and its ability to be engineered structurally and chemically at nano-, micro-, and macroscales. Its high water content and purity make the material biocompatible for multiple medical applications. Its biocompatibility, mechanical strength, chemical and morphologic controllability make it a natural choice for use in the body in biomedical devices with broader application than has yet been utilized. This paper reviews the current state of understanding of bacterial cellulose, known methods for controlling its physical and chemical structure (e.g., porosity, fiber alignment, etc.), biomedical applications for which it is currently being used, or investigated for use, challenges yet to be overcome, and future possibilities for BC.

Nyckelord: Bacterial cellulose, Microbial cellulose, Nanocellulose, Biocompatibility, Biomedical, Acetobacter xylinum, biomedical applications, microbial cellulose, biomimetic synthesis, agitated culture, abdominal-wall, tissue, bone, biocompatibility, proliferation, scaffolds, ntana jd, 1990, v24-5, p253



Denna post skapades 2011-09-01.
CPL Pubid: 145686

 

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Institutioner (Chalmers)

Institutionen för kemi- och bioteknik, Polymerteknologi (2005-2014)

Ämnesområden

Kemi

Chalmers infrastruktur