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The total branch length of sample genealogies in populations of variable size

Anders Eriksson ; Bernhard Mehlig ; Marina Rafajlovic ; Serik Sagitov (Institutionen för matematiska vetenskaper, matematisk statistik)
Genetics (0016-6731). Vol. 186 (2010), 2, p. 601-611.
[Artikel, refereegranskad vetenskaplig]

We consider neutral evolution of a large population subject to changes in its population size. For a population with a time-variable carrying capacity we study the distribution of the total branch lengths of its sample genealogies. Within the coalescent approximation we have obtained a general expression— Equation 20—for the moments of this distribution with a given arbitrary dependence of the population size on time. We investigate how the frequency of population-size variations alters the total branch length.

Nyckelord: population-size fluctuations, population homozygosity, genealogy, single nucleotide polymorphism, coalescent approximation, statistical tests, varying size, coalescent, evolution



Denna post skapades 2011-08-29. Senast ändrad 2016-07-11.
CPL Pubid: 145325

 

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Institutioner (Chalmers)

Institutionen för fysik (GU) (GU)
Institutionen för matematiska vetenskaper, matematisk statistik (2005-2016)

Ämnesområden

Matematisk statistik
Genetik

Chalmers infrastruktur