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Probing DNA conductivity with photoinduced electron transfer and scanning tunneling microscopy

Eimer Tuite (Institutionen för fysikalisk kemi) ; Per Lincoln (Institutionen för fysikalisk kemi) ; Johan Olofsson (Institutionen för fysikalisk kemi) ; Hans-Christian Becker (Institutionen för fysikalisk kemi) ; Björn Önfelt (Institutionen för fysikalisk kemi) ; D. Erts ; Bengt Nordén (Institutionen för fysikalisk kemi)
Journal of Biomolecular Structure & Dynamics. 11th Conversation in Biomolecular Stereodynamics. Suny Albany, Albany, New York, JUN 15-19, 1999 (0739-1102). p. 277-283. (2000)
[Konferensbidrag, refereegranskat]

The possibility that the stacked DNA bases can mediate vectorial electron transfer has been examined using two different approaches. Experiments on photoinduced electron transfer with intercalated donors and accepters (either randomly bound or linked dyads of ruthenium complex and viologen) indicate that while DNA may be a better medium than acetonitrile for electron transfer over short distances (2-3-base pair, equivalent to 10-14 Angstrom centre-to-centre separation), it is a poor medium for transport over larger separations. Attempts to measure conductivity of individual DNA molecules using scanning tunneling microscopy to image mixed monolayers of mercaptohexanol (MCH) and 30-mer or 10-mer DNAs with alkanethiol linkers also indicate that DNA in its native state is a poor conductor. AFM images of the DNA/MCH mixed monolayers show that the DNA molecules extend vertically upward from the surface in such surface architectures.

Denna post skapades 2011-06-20.
CPL Pubid: 142018


Institutioner (Chalmers)

Institutionen för fysikalisk kemi (1900-2003)


Fysikalisk kemi

Chalmers infrastruktur