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Exact equilibrium state solution of an intracellular complex formation model: kA↔P reaction in a small volume

Zoran Konkoli (Institutionen för mikroteknologi och nanovetenskap, Bionanosystem)
Physical Review E (1539-3755 ). Vol. 82 (2010), 4, p. 041922 .
[Artikel, refereegranskad vetenskaplig]

A generic model of complex formation in small volumes was studied under the assumption of perfect mixing. Particles A react in clusters, and each reaction converts k A particles into a P particle. The back reaction is also allowed. The equilibrium state of the model is solved exactly. Fluctuations in product particle number are reduced by increasing the degree of cooperativity k. Three qualitatively distinct reactant fluctuation characteristics emerge.

Nyckelord: well stirred reaction volume, complex formation, noise characteristics



Denna post skapades 2010-10-04. Senast ändrad 2011-04-29.
CPL Pubid: 127217

 

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Institutioner (Chalmers)

Institutionen för mikroteknologi och nanovetenskap, Bionanosystem (2007-2015)

Ämnesområden

Statistisk fysik
Makromolekylfysik
Biologisk fysik
Molekylärbiologi
Cellbiologi

Chalmers infrastruktur