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Carbon nanotubes towards medicinal biochips

A. O. Tarakanov ; L. B. Goncharova ; Yury A. Tarakanov (Institutionen för teknisk fysik, Kondenserade materiens teori)
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology (1939-5116). Vol. 2 (2010), 1, p. 1-10.
[Artikel, refereegranskad vetenskaplig]

Carbon nanotubes (CNTs) exhibit a unique combination of biological and physical properties.(1-3) These properties make CNT-based devices, especially CNT field-effect transistors (FETs),(3,4) promising as a novel platform for chemical sensors,(5) biosensors,(6-8) and biochips.(9-11) The last ones seem to be especially promising for clinical diagnostics.(12) Namely, biochips permit the analysis of DNA, proteins, and other biological and chemical molecules in a massively parallel format.(13) They represent a multidisciplinary development unifying molecular biology, chemical and electronics engineering.(14) The emerging technologies of CNT biochips in medicine might provide further advantages relative to traditional biochip platforms including the cost and speed of medical tests.(12,15,16) Accordingly, our overview focuses on the recent advances in CNT-based biochips and tries to clarify their medicinal potential including lab-on-chips for molecular diagnostics,(17,18) drug screening,(19) and also novel strategies in molecular medicine.(20-22)

Nyckelord: PROTEIN-COUPLED RECEPTORS, FIELD-EFFECT TRANSISTORS, HUMAN GENOME, PARKINSONS-DISEASE, ARRAY BIOSENSOR, DRUG DISCOVERY, LIPID-BILAYERS, SINGLE-WALL, DOPAMINE, ACID



Denna post skapades 2010-05-12. Senast ändrad 2013-05-22.
CPL Pubid: 121543

 

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Institutioner (Chalmers)

Institutionen för teknisk fysik, Kondenserade materiens teori (1900-2015)

Ämnesområden

Medicinsk teknik

Chalmers infrastruktur