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Assessment of fracture risk.

John A Kanis ; Frederik Borgstrom ; Chris De Laet ; Helena Johansson ; Olof Johnell ; Bengt Jonsson ; Anders Odén (Institutionen för matematiska vetenskaper, matematisk statistik) ; Niklas Zethraeus ; Bruce Pfleger ; Nikolai Khaltaev
Osteoporosis international (0937-941X). Vol. 16 (2005), 6, p. 581-9.
[Artikel, refereegranskad vetenskaplig]

The diagnosis of osteoporosis is based on the measurement of bone mineral density (BMD). There are a number of clinical risk factors that provide information on fracture risk over and above that given by BMD. The assessment of fracture risk thus needs to be distinguished from diagnosis to take account of the independent value of the clinical risk factors. These include age, a prior fragility fracture, a parental history of hip fracture, smoking, use of systemic corticosteroids, excess alcohol intake and rheumatoid arthritis. The independent contribution of these risk factors can be integrated by the calculation of fracture probability with or without the use of BMD. Treatment can then be offered to those identified to have a fracture probability greater than an intervention threshold.

Nyckelord: Adult, Age Factors, Aged, Alcohol Drinking, Arthritis, Rheumatoid, complications, drug therapy, Female, Fractures, Bone, etiology, genetics, Glucocorticoids, adverse effects, therapeutic use, Humans, Male, Middle Aged, Osteoporosis, complications, diagnosis, genetics, Recurrence, Risk Assessment, Smoking, adverse effects



Denna post skapades 2010-01-09. Senast ändrad 2010-01-26.
CPL Pubid: 106051

 

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Institutioner (Chalmers)

Institutionen för samhällsmedicin, Avdelningen för geriatrik (1900-2005)
Institutionen för matematiska vetenskaper, matematisk statistik (2005-2016)

Ämnesområden

Klinisk fysiologi
Endokrinologi

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