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A comparison between the transfer function of ABP to ICP and compensatory reserve index in TBI

Sima Shahsavari (Institutionen för signaler och system, Signalbehandling) ; Tomas McKelvey (Institutionen för signaler och system, Signalbehandling) ; T. Skoglund ; C. Ritzèn
Acta neurochirurgica. Supplement (00651419 (ISSN)). Vol. 102 (2008), p. 9-13.
[Artikel, refereegranskad vetenskaplig]

BACKGROUND: The transfer functions which map the arterial blood pressure to the intracranial pressure and the compensatory reserve index have been investigated by various groups to evaluate the brain compliance of patients with traumatic brain injury. The focus of this study has been to assess the capability of both the above mentioned methods to monitor the intracranial compliance in patients suffering from brain swelling. MATERIALS AND METHODS: Clinical data was collected from sixteen traumatic brain injury patients and split into 4 min segments. For each segment, both the magnitude of the empirical transfer function at the fundamental cardiac frequency and the compensatory reserve index were extracted. FINDINGS: The mean values of the compensatory reserve index and the magnitude of the transfer function which scored higher than 0.7 and 0.1 respectively were recorded for all patients suffering from brain swelling. By comparing the histogram of the magnitude of the transfer function at the fundamental cardiac frequency with the histogram of the compensatory reserve index for all patients, a positive correlation between the mean values and a negative correlation among their variances were observed. The linear correlation between the mean values was estimated at r = 0.82 (p < 0.0001). CONCLUSIONS: These observations suggest that to evaluate the intracranial compensatory reserve, the magnitude of 0.1 could be a useful threshold for the transfer function at the fundamental cardiac frequency.

Nyckelord: adolescent, adult, aged, article, blood pressure, brain circulation, brain injury, comparative study, female, hospitalization, human, intracranial pressure, male, middle aged, pathophysiology, physiology, signal processing, time, Brain Injuries, Cerebrovascular Circulation, Humans, Severity of Illness Index, Signal Processing, Computer-Assisted, Time Factors, Young Adult



Denna post skapades 2009-10-23. Senast ändrad 2016-07-22.
CPL Pubid: 100679

 

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Institutioner (Chalmers)

Institutionen för signaler och system, Signalbehandling

Ämnesområden

Information Technology

Chalmers infrastruktur